Case 182

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Since low birth weight is a leading cause of infant mortality,7 varying rates of this outcome among Hispanic subgroups may translate to similarly varying patterns in infant mortality. On the other hand, if access to neonatal intensive care services differs by maternal birthplace or ethnicity, then infant mortality rates might not reflect differences in low-birth-weight rates among Hispanic subg...

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Evaluation of drug-drug interaction (DDI) involving circulating inhibitory metabolites of perpetrator drugs has recently drawn more attention from regulatory agencies and pharmaceutical companies. Here, using amiodarone (AMIO) as an example, we demonstrate the use of physiologically based pharmacokinetic (PBPK) modeling to assess how a potential inhibitory metabolite can contribute to clinicall...

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ژورنال

عنوان ژورنال: Radiology

سال: 2012

ISSN: 0033-8419,1527-1315

DOI: 10.1148/radiol.11103539